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Correspondence
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Volume 343:1270-1271 October 26, 2000 Number 17
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A Patient with Myeloid Metaplasia of the Skin and Mouth

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 by Kessler, D. A.
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 by Tefferi, A.
To the Editor: Post-polycythemic myeloid metaplasia is characterized by increasing splenomegaly, dacryocytes, anemia, extensive bone marrow fibrosis, and a leukoerythroblastic blood picture.1 We describe a patient with post-polycythemic myeloid metaplasia in whom mucocutaneous myeloid metaplasia developed during treatment with epoetin.

In 1990, myeloid metaplasia developed in a 74-year-old man with a history of polycythemia vera and a history of splenectomy after abdominal trauma. Anemia developed that did not respond to treatment with hydroxyurea, danazol, and epoetin (10,000 U subcutaneously three times a week) and that became transfusion-dependent in December 1994. In December 1997, the patient underwent an abdominal hernia repair . . . [Full Text of this Article]

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