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Correspondence
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Volume 343:147-148 July 13, 2000 Number 2
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Exercise and Coronary Endothelial Function

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 by Hambrecht, R.
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To the Editor: Hambrecht and colleagues (Feb. 17 issue)1 report that exercise training improves endothelial function in the coronary circulation. In their discussion of the potential mechanisms involved, the authors correctly point out that the recruitment of collateral vessels may enhance coronary blood flow in ischemic areas of the myocardium. However, they state that although there is evidence that exercise training improves collateral circulation in animals, such angiographic evidence is lacking in humans.

The authors fail to mention that there is angiographic evidence of improvement in the collateral circulation after exercise training in patients with coronary artery disease. We recently . . . [Full Text of this Article]

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