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Correspondence
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Volume 343:1656-1657 November 30, 2000 Number 22
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Hepatic Iron Concentration and Total Body Iron Stores in Thalassemia Major

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by Angelucci, E.
To the Editor: The study by Angelucci et al. (Aug. 3 issue)1 provides useful evidence that the estimated hepatic iron concentration is an indirect measure of total mobilizable body iron stores, but the authors misinterpreted the results of our study.2 The main point of our study was that magnetic resonance imaging (MRI) techniques that use a gradient–echo sequence with a flip angle of 10 degrees and short repetition and echo times do make possible the accurate, noninvasive estimation of hepatic iron concentrations. Our results extend the results of other studies demonstrating the value of such special MRI algorithms for the . . . [Full Text of this Article]

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