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Volume 343:1894-1896 December 21, 2000 Number 25
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Pravastatin Therapy and the Risk of Stroke

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by White, H. D.
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To the Editor: In their discussion of pravastatin therapy to reduce the risk of stroke, White et al. (Aug. 3 issue)1 cite several references erroneously and present their findings without appropriate qualifying language.

First, they note that "several trials of . . . statins have reported reductions of 25 to 30 percent in the rate of stroke." To support this statement, they cite four references, three of which report on specific clinical trials. However, one of those trials (the West of Scotland study) showed no reduction in the rate of stroke; the risk after five years of follow-up was reported . . . [Full Text of this Article]

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