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Previous Volume 343:219-220 July 20, 2000 Number 3 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: On the basis of their population-based, case–control study of invasive pneumococcal disease, Nuorti and coworkers (March 9 issue)¹ conclude that cigarette smoking is the strongest independent risk factor for invasive disease in immunocompetent persons between the ages of 18 and 64 years. Unfortunately, the authors did not adequately address the role of undiagnosed human immunodeficiency virus (HIV) infection as a risk factor for pneumococcal disease or as a potential confounder of the observed association between smoking and invasive pneumococcal infection.

As Nuorti and colleagues recently reported in another article, communities with a high prevalence of HIV infection, . . . [Full Text of this Article]

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