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Correspondence
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Volume 343:220-221 July 20, 2000 Number 3
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Coagulation Factor XI and Venous Thrombosis

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 by Meijers, J. C.M.
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To the Editor: Meijers et al. (March 9 issue),1 who report that high levels of coagulation factor XI are a risk factor for deep venous thrombosis, did not take into account the possible role of antiphospholipid antibodies. During the past decade, the antiphospholipid-antibody syndrome has been recognized as one of the most common types of acquired thrombophilia. According to the international consensus statement on preliminary classification criteria for definite antiphospholipid syndrome, the syndrome is defined by the presence of antiphospholipid antibodies or lupus anticoagulant and a history of arterial, venous, or small-vessel thrombosis or pregnancy-related morbidity.2

The risk of recurrent . . . [Full Text of this Article]

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