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The thinking that distinguishes biology from other sciences originated in the 19th century with Darwin's appreciation that members of all species exhibit phenotypic variation. This led to the idea that change in external circumstances would favor some phenotypes over others and that such selection could in time result in the evolution of new species. In the 20th century, biology attracted many chemists and physicists. Rather than observe organisms, they broke them into components, which they then studied in great detail. By necessity, this reductionist approach could be used with only a few species, but that was of little concern, because
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