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Review Article
Drug Therapy
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Volume 344:38-47 January 4, 2001 Number 1
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Misoprostol and Pregnancy
Alisa B. Goldberg, M.D., Mara B. Greenberg, B.S., and Philip D. Darney, M.D.

Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Commentary
-Editorial
 by Hale, R. W.

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Misoprostol is a prostaglandin E1 analogue that has been approved by the Food and Drug Administration (FDA) to be taken orally for the prevention and treatment of gastric ulcers associated with the use of nonsteroidal antiinflammatory drugs. It has also become an important drug in obstetrical and gynecologic practice because of its uterotonic and cervical-ripening actions. Misoprostol is useful for elective medical abortion, cervical ripening before surgical abortion, evacuation of the uterus in cases of embryonic or fetal death, and induction of labor. The drug may also be used to treat and even prevent postpartum hemorrhage. However, misoprostol is not . . . [Full Text of this Article]

Pharmacokinetics, Physiology, and Teratogenicity

Misoprostol in the First Trimester of Pregnancy

Medical Abortion

Failed Pregnancy or Fetal Death

Cervical Ripening before Surgical Abortion

Misoprostol in the Second Trimester of Pregnancy

Abortion

Misoprostol in the Third Trimester of Pregnancy

Induction of Labor with a Viable Fetus

Induction of Labor after Fetal Death

Induction of Labor in Women with Previous Cesarean Delivery

Misoprostol for Postpartum Hemorrhage

Conclusions


Source Information

From the Department of Obstetrics, Gynecology, and Reproductive Sciences, Center for Reproductive Health Research and Policy, San Francisco General Hospital and the University of California, San Francisco.

Address reprint requests to Dr. Goldberg at the Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, San Francisco General Hospital, 1001 Potrero Ave. Ward 6D-11, San Francisco, CA 94110.

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