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Images in Clinical Medicine
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Volume 344:815 March 15, 2001 Number 11
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Paclitaxel and Cell Division

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A 47-year-old woman had been given a diagnosis of a malignant ovarian tumor in 1995. Initial treatment included a radical hysterectomy and postoperative chemotherapy with cisplatin and radiotherapy of the pelvis. Diffuse peritoneal relapse of the tumor was diagnosed in 1997, and treatment with paclitaxel and carboplatin was begun. Because of diarrhea, upper endoscopy and colonoscopy were performed while the patient was receiving a 24-hour infusion of paclitaxel. The last dose of carboplatin had been given one month earlier, and the next dose was to be given hours after endoscopy. Upper endoscopy showed proximal submucosal hemorrhage of the stomach and . . . [Full Text of this Article]

 

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