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Correspondence
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Volume 344:858-859 March 15, 2001 Number 11
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Case 30-2000: Churg–Strauss Syndrome

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To the Editor: Dr. Arm's discussion (Sept. 28 issue)1 of a case of the Churg–Strauss syndrome in a man who was receiving multiple asthma medications, including montelukast (Singulair, Merck), did not include important medical history. Information received through our pharmacovigilance program indicates that, before treatment with montelukast was started, the patient had recurrent bilateral pulmonary infiltrates and an ill-defined episode of asthma, diarrhea, weight loss, anemia, and pleural effusion, which responded rapidly to treatment with high doses of corticosteroids. All this suggests that the patient had a forme fruste of the Churg–Strauss syndrome before the initiation of montelukast.

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