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Clinical Practice
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Volume 344:1373-1377 May 3, 2001 Number 18
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Prostate-Specific–Antigen Testing for Early Diagnosis of Prostate Cancer
Michael J. Barry, M.D.

Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Commentary
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 by Lee, T. H.

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This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author's clinical recommendations.

A 65-year-old man with no risk factors for prostate cancer except his age has a normal digital rectal examination. Should a prostate-specific–antigen (PSA) test be ordered?

The Clinical Problem

The introduction of PSA testing in 1987 resulted in an enormous increase in the reported incidence of prostate cancer in the United States. After peaking in 1992, the incidence fell, presumably owing to the identification of . . . [Full Text of this Article]

The PSA Test

Tests That May Improve the Performance of the PSA Test

Screening Interval

Strategies and Evidence

Areas of Uncertainty

Guidelines

Conclusions and Recommendations


Source Information

From the Medical Practices Evaluation Center, Massachusetts General Hospital, and the Department of Medicine, Harvard Medical School — both in Boston.

Address reprint requests to Dr. Barry at the Medical Practices Evaluation Center, Massachusetts General Hospital, 50 Staniford St., 9th Fl., Boston, MA 02114.

References


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