This Journal feature begins with a case vignette highlightinga common clinical problem. Evidence supporting various strategiesis then presented, followed by a review of formal guidelines,when they exist. The article ends with the author's clinicalrecommendations.
A 65-year-old man with no risk factors for prostate cancer excepthis age has a normal digital rectal examination. Should a prostate-specificantigen(PSA) test be ordered?
The Clinical Problem
The introduction of PSA testing in 1987 resulted in an enormousincrease in the reported incidence of prostate cancer in theUnited States. After peaking in 1992, the incidence fell, presumablyowing to the identification of . . . [Full Text of this Article]
The PSA Test
Tests That May Improve the Performance of the PSA Test
Screening Interval
Strategies and Evidence
Areas of Uncertainty
Guidelines
Conclusions and Recommendations
Source Information
From the Medical Practices Evaluation Center, Massachusetts General Hospital, and the Department of Medicine, Harvard Medical School both in Boston.
Address reprint requests to Dr. Barry at the Medical Practices Evaluation Center, Massachusetts General Hospital, 50 Staniford St., 9th Fl., Boston, MA 02114.
References
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