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Editorial
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Volume 344:1390-1392 May 3, 2001 Number 18
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Changing Habits to Delay Diabetes

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 by Tuomilehto, J.
For centuries, fatter and more sedentary people have been considered more likely to get diabetes. More recently, many prospective studies have established that obesity and physical inactivity are risk factors for type 2 diabetes mellitus1 and that weight loss and exercise improve insulin sensitivity and insulin secretion in the short term. Two studies, in subjects in Sweden and China, have indicated that changes in diet and in exercise habits might delay the onset of diabetes.2,3 However, because these studies had methodologic weaknesses (one was not randomized, and in the other, clinics rather than individual subjects were randomized), it has remained . . . [Full Text of this Article]

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