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Previous Volume 344:1556 May 17, 2001 Number 20 Next

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To the Editor: The study by Glaser et al. (Jan. 25 issue)¹ identified risk factors for the development of symptomatic cerebral edema in children with diabetic ketoacidosis. Of the 61 children in whom symptomatic cerebral edema developed, 57 percent recovered completely, 21 percent had permanent neurologic damage, and 21 percent died. The investigators did not identify the risk factors for death from cerebral herniation or for permanent neurologic damage. It would be clinically relevant to compare the children who died or had permanent neurologic damage with those who did not have symptomatic cerebral edema or who had symptomatic cerebral edema . . . [Full Text of this Article]

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