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Previous Volume 344:1676-1679 May 31, 2001 Number 22 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text PDF Editorial by Monaco, A. P. Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited PubMed Citation

Total laryngectomy and total occlusion of the larynx with tracheostomy are associated with an impaired sense of taste and smell, an increased incidence of tracheobronchial infections, stomal encrustations, loss of nasal respiration, and loss of a human-sounding voice. A fundamental consideration in treating a patient whose larynx has been irreparably damaged is whether the goals of surgery should include replacement of the larynx to improve the patient's quality of life. An early attempt to treat laryngeal cancer with a partial laryngeal transplant¹ was accompanied by rapid recurrence of the tumor, an outcome that quashed interest in the procedure for nearly . . . [Full Text of this Article]

Case Report

The Patient and the Donor

Surgical Procedure

Postoperative Course

Results

Voice Quality

Respiration and Swallowing

Infection

Thyroid Effects

Discussion

Source Information

From the Departments of Otolaryngology (M.S., J.S., R.E., D.H., R.R.L., I.E.), Nephrology and Hypertension (W.B.), and Plastic and Reconstructive Surgery (R.Y.), Cleveland Clinic Foundation, Cleveland; and Lifelink Transplant Institute, Tampa, Fla. (J.M.).

Address reprint requests to Dr. Strome at the Department of Otolaryngology, Cleveland Clinic Foundation, 9500 Euclid Ave., Cleveland, OH 44195.

References

This article has been cited by other articles:

• Dubernard, J.-M., Lengele, B., Morelon, E., Testelin, S., Badet, L., Moure, C., Beziat, J.-L., Dakpe, S., Kanitakis, J., D'Hauthuille, C., El Jaafari, A., Petruzzo, P., Lefrancois, N., Taha, F., Sirigu, A., Di Marco, G., Carmi, E., Bachmann, D., Cremades, S., Giraux, P., Burloux, G., Hequet, O., Parquet, N., Frances, C., Michallet, M., Martin, X., Devauchelle, B. (2007). Outcomes 18 Months after the First Human Partial Face Transplantation. NEJM 357: 2451-2460 [Abstract] [Full Text]  
• Jaillard, S., Holder-Espinasse, M., Hubert, T., Copin, M.-C., Duterque-Coquillaud, M., Wurtz, A., Marquette, C.-H. (2006). Tracheal replacement by allogenic aorta in the pig.. Chest 130: 1397-1404 [Abstract] [Full Text]  
• Tintinago, L. F., Herrera, D. A., Medina, E., Patino, J. H., Cano, F., Restrepo, C. S. (2005). Ultrasonographic Evaluation of a Vascularized Tracheal Transplantation. J Ultrasound Med 24: 1145-1149 [Full Text]  
• Zeitels, S. M., Healy, G. B. (2003). Laryngology and Phonosurgery. NEJM 349: 882-892 [Full Text]  
• Hettiaratchy, S., Butler, P. E M (2003). Extending the boundaries of transplantation. BMJ 326: 1226-1227 [Full Text]  
• Furlan, J. C., Brandao, L. G., Ferraz, A. R., Rodrigues, A. J. Jr (2003). Surgical Anatomy of the Extralaryngeal Aspect of the Superior Laryngeal Nerve. Arch Otolaryngol Head Neck Surg 129: 79-82 [Abstract] [Full Text]  
• Brenner, M. J., Tung, T. H., Jensen, J. N., Mackinnon, S. E. (2002). The Spectrum of Complications of Immunosuppression: Is the Time Right for Hand Transplantation?. JBJS 84: 1861-1870 [Full Text]  
• Grillo, H. C. (2002). Tracheal replacement: a critical review. Ann. Thorac. Surg. 73: 1995-2004 [Abstract] [Full Text]  
• Monaco, A. P. (2001). Transplantation of the Larynx -- A Case Report That Speaks for Itself. NEJM 344: 1712-1714 [Full Text]