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Editorial
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Volume 344:1942-1944 June 21, 2001 Number 25
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The Power of Genetics to Target Surgical Prevention

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 by Huntsman, D. G.
-PubMed Citation
Dramatic advances in our understanding of the genetic basis of cancer have led to new forms of technology and new tools for assessing the genetic risk of cancer. In this issue of the Journal, Huntsman et al.1 report the experience of two families with hereditary diffuse gastric cancer, before and after definitive genetic testing was available. Their stories illustrate key issues in the assessment of the genetic risk of cancer.

Although inherited forms of cancer are rare — representing only about 5 percent of many types of adult-onset cancer — the risks conferred by the inherited cancer-susceptibility genes are high . . . [Full Text of this Article]

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