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Editorial
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Volume 344:302-303 January 25, 2001 Number 4
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Predicting Cerebral Edema during Diabetic Ketoacidosis

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 by Glaser, N.
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Cerebral edema is a devastating complication of diabetic ketoacidosis and remains the leading cause of serious illness and death in children with diabetes mellitus.1 The causes of cerebral edema are unknown, largely because of the lack of large-scale population-based studies. However, several hypotheses relating to possible antecedent risk factors and the effects of various treatment regimens have been proposed.1

In this issue of the Journal, Glaser et al.2 report the results of a retrospective analysis of cases of children with diabetic ketoacidosis at 10 centers. Among 6977 such children, the authors identified 61 with cerebral edema. The incidence of cerebral . . . [Full Text of this Article]

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