Cerebral edema is a devastating complication of diabetic ketoacidosisand remains the leading cause of serious illness and death inchildren with diabetes mellitus.1 The causes of cerebral edemaare unknown, largely because of the lack of large-scale population-basedstudies. However, several hypotheses relating to possible antecedentrisk factors and the effects of various treatment regimens havebeen proposed.1
In this issue of the Journal, Glaser et al.2 report the resultsof a retrospective analysis of cases of children with diabeticketoacidosis at 10 centers. Among 6977 such children, the authorsidentified 61 with cerebral edema. The incidence of cerebral. . . [Full Text of this Article]
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