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Correspondence
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Volume 344:532-533 February 15, 2001 Number 7
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Transplantation of a Tissue-Engineered Pulmonary Artery

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To the Editor: Various vascular grafts are commonly used in the reconstruction of cardiovascular tissues. However, prosthetic or bioprosthetic materials lack growth potential and therefore in children require replacement as the children grow. Tissue engineering offers the potential to create replacement structures from autologous cells and biodegradable polymer scaffolds. Since they contain living cells, these structures have the potential to grow, to repair themselves, and to remodel themselves.1,2,3,4

A four-year-old girl had been found to have a single right ventricle and pulmonary atresia and had undergone pulmonary-artery angioplasty and the Fontan procedure at the age of three years, three months. . . . [Full Text of this Article]

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