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Correspondence
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Volume 344:689-690 March 1, 2001 Number 9
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Adjuvant Chemotherapy for Completely Resected Non–Small-Cell Lung Cancer

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To the Editor: In a randomized trial, three quantities related to sample size must be defined so as to ensure small enough error rates to make the conclusions credible: the significance level ({alpha}), the power of a test for a particular alternative hypothesis (1–{beta}), and the difference one wishes to detect ({delta}). Since only the P value ({alpha}) is specified in the study by Keller et al. on adjuvant chemotherapy for completely resected non–small-cell lung cancer (Oct. 26 issue),1 the negative results could be due to the use of a sample that was insufficiently large to . . . [Full Text of this Article]

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