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Previous Volume 345:64-66 July 5, 2001 Number 1 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Högenauer and colleagues (Jan. 25 issue)¹ report on a patient with intermittent severe diarrhea and malabsorption, which lasted several months and "improved spontaneously." There was no increase in serum cholecystokinin levels, and no endocrine cells could be demonstrated on one occasion by immunohistochemical studies in biopsy specimens of the duodenal mucosa. The authors concluded that the diarrhea and severe malabsorption were caused by a deficiency of cholecystokinin-producing enteroendocrine cells in the mucosa of the patient's proximal small intestine.

A deficiency of gut hormones can be experimentally induced by several means: the suppression of hormone secretion by somatostatin, . . . [Full Text of this Article]

References

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