To the Editor: As a group, fat-soluble vitamins are lifesavingat physiologic levels and dangerous at megavitamin levels.1For many people the word "vitamin" implies something that isbeneficial and essential, not potentially poisonous.2 More thanone third of people in the United States regularly use dietarysupplements.3 We describe a patient with hypercalcemia associatedwith the ingestion of an over-the-counter vitamin D supplement.
A 42-year-old man was hospitalized with symptoms of hypercalcemiaof a few weeks' duration. For the past two years, he had beentaking a supplement that contained vitamin D3. On admissionhis serum levels were . . . [Full Text of this Article]
References
This article has been cited by other articles:
Holick, M. F.
(2007). Vitamin D Deficiency. NEJM
357: 266-281
[Full Text]
Klontz, K. C., Acheson, D. W.
(2007). Dietary Supplement-Induced Vitamin D Intoxication. NEJM
357: 308-309
[Full Text]
Shinchuk, L., Holick, M. F.
(2007). Vitamin D and Rehabilitation: Improving Functional Outcomes. Nutr Clin Pract
22: 297-304
[Abstract][Full Text]
Hathcock, J. N, Shao, A., Vieth, R., Heaney, R.
(2007). Risk assessment for vitamin D. Am. J. Clin. Nutr.
85: 6-18
[Abstract][Full Text]
Vieth, R.
(2006). Critique of the Considerations for Establishing the Tolerable Upper Intake Level for Vitamin D: Critical Need for Revision Upwards. J. Nutr.
136: 1117-1122
[Abstract][Full Text]
Leventis, P., Garrison, L., Sibley, M., Peterson, P., Egerton, M., Levin, G., Kiely, P.
(2005). Underestimation of Serum 25-Hydroxyvitamin D by the Nichols Advantage Assay in Patients Receiving Vitamin D Replacement Therapy. Clin. Chem.
51: 1072-1074
[Full Text]