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Editorial
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Volume 345:1057-1059 October 4, 2001 Number 14
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Acute Coronary Syndromes — Beyond Myocyte Necrosis

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The acute coronary syndromes, which comprise unstable angina, myocardial infarction without ST-segment elevation, and myocardial infarction with ST-segment elevation, continue to be a major health problem. Recent important advances in revascularization techniques, such as the advent of coronary-artery stenting, have been paralleled by developments in drug treatment. A typical approach to the acute coronary syndromes includes multiple treatment options: aspirin, beta-blockers, nitrates, unfractionated heparin, low-molecular-weight heparin, intravenous glycoprotein IIb/IIIa receptor inhibitors, clopidogrel, coronary stenting, thrombolytic agents, statins, and angiotensin-converting–enzyme (ACE) inhibitors. Therefore, one of the most important challenges in this era of cost containment is to identify the subgroup of . . . [Full Text of this Article]

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