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Previous Volume 345:1331-1335 November 1, 2001 Number 18 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Recovery from an infectious disease or an encounter with a nonmicrobial antigen is usually followed by the development of resistance to that disease or a rapid and heightened immune response on reexposure to the antigen. These effects, termed immunologic memory, are explainable by the generation of increased numbers of precursor lymphocytes during the initial encounter and the induction of a special "memory" quality of individual T and B cells.^1,2,3,4 Alternatively, memory could result from the persistence of low levels of antigen in lymphoid tissues, which keep T cells activated and maintain protective amounts of antibodies.^5,6 In this article, I will . . . [Full Text of this Article]

Transferable Maternal Immune Protection

The Host–Parasite Equilibrium

The Role of Hygiene

Maternal Immunity and Autoimmune Diseases

Conclusions

Source Information

From the Institute of Experimental Immunology, University Hospital, Zurich, Switzerland.

Address reprint requests to Dr. Zinkernagel at the Institute of Experimental Immunology, University Hospital, CH-8091 Zurich, Switzerland, or at rolf.zinkernagel@pty.usz.ch.

References

Related Letters:

Childhood Infections and Autoimmune Diseases
Vento S., Cainelli F., Lemke H., Lange H., Zinkernagel R. M.
Extract | Full Text | PDF  
N Engl J Med 2002; 346:1749-1750, May 30, 2002. Correspondence

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