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Correspondence
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Volume 345:146-147 July 12, 2001 Number 2
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Transplantation of Embryonic Dopamine Neurons for Severe Parkinson's Disease

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To the Editor: The study of the transplantation of embryonic dopamine neurons for severe Parkinson's disease reported by Freed et al. (March 8 issue)1 revealed no benefit as measured on the basis of the primary outcome variable. In addition, severe dyskinesias developed in some patients. We believe it is important to not rush to judgment in evaluating neuronal transplantation in Parkinson's disease on the basis of the results of a single study.

The outcome variable — a subjective global rating of the change in the severity of the disease — was assessed with the use of a scale that was . . . [Full Text of this Article]

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