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Review Article
Current Concepts
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Volume 345:1465-1472 November 15, 2001 Number 20
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Chronic Thromboembolic Pulmonary Hypertension
Peter F. Fedullo, M.D., William R. Auger, M.D., Kim M. Kerr, M.D., and Lewis J. Rubin, M.D.

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Thromboembolic obstruction of the major pulmonary arteries due to unresolved pulmonary embolism is a potentially correctable cause of pulmonary hypertension. Chronic thromboembolic pulmonary hypertension of sufficient severity to warrant surgical intervention is more common than previously suspected. Each year, there are 500 to 2500 patients with this condition in the United States, accounting for 0.1 to 0.5 percent of patients with pulmonary emboli who survive.1,2 The diagnosis and management of chronic thromboembolic pulmonary hypertension require a multidisciplinary approach involving the specialties of surgery, pulmonary medicine, critical care, cardiology, anesthesiology, and radiology. With this approach, pulmonary thromboendarterectomy can be performed with . . . [Full Text of this Article]

Epidemiology and Pathophysiology

Clinical Manifestations

Treatment and Prognosis


Source Information

From the Department of Medicine, Division of Pulmonary and Critical Care, University of California, San Diego, Medical Center, 9300 Campus Point Dr., MC 7372, La Jolla, CA 92037-1300, where reprint requests should be addressed to Dr. Rubin.

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