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Previous Volume 345:1498-1500 November 15, 2001 Number 20 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: At first glance, the data of Meijers-Heijboer and colleagues (July 19 issue)¹ appear to support the position that prophylactic mastectomy reduces the risk of breast cancer in carriers of a BRCA mutation. On close reading of the article, however, I find that very little support for this position is presented. The authors report no new cases of breast cancer after a mean of 2.9 years in a cohort of 76 women who underwent mastectomy. This is to be expected, however; no breast cancers were detected on pathological review of the corresponding specimens, and it is exceedingly unlikely . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Russo, J., Mailo, D., Hu, Y.-F., Balogh, G., Sheriff, F., Russo, I. H. (2005). Breast Differentiation and Its Implication in Cancer Prevention. Clin. Cancer Res. 11: 931s-936s [Abstract] [Full Text]