FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 345:1568-1569 November 22, 2001 Number 21 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text PDF Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited Related Article by Gortmaker, S. L. PubMed Citation

It has been nearly 20 years since the first cases of AIDS were reported in children in the United States, and the face of pediatric human immunodeficiency virus type 1 (HIV-1) infection has changed markedly. During the first 15 years of the epidemic, approximately 15,000 infants acquired HIV-1 infection in the United States, mainly through vertical, or mother-to-child, transmission of the virus.¹ Over the same period, about 3000 children died of AIDS. More recently, the development of effective prophylactic and therapeutic strategies has markedly reduced the number of newly infected infants and has changed clinical outcomes in infected children.

In . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Hazra, R., Stoszek, S. K, Freimanis Hance, L., Pinto, J., Marques, H., Peixoto, M., Alarcon, J., Mussi-Pinhata, M., Serchuck, L., for the NISDI Pediatric Study Group 2008, (2009). Cohort Profile: NICHD International Site Development Initiative (NISDI): a prospective, observational study of HIV-exposed and HIV-infected children at clinical sites in Latin American and Caribbean countries. Int J Epidemiol 38: 1207-1214 [Full Text]  
• Berk, D. R., Falkovitz-Halpern, M. S., Hill, D. W., Albin, C., Arrieta, A., Bork, J. M., Cohan, D., Nilson, B., Petru, A., Ruiz, J., Weintrub, P. S., Wenman, W., Maldonado, Y. A., for the California Pediatric HIV Study Group, (2005). Temporal Trends in Early Clinical Manifestations of Perinatal HIV Infection in a Population-Based Cohort. JAMA 293: 2221-2231 [Abstract] [Full Text]  
• Feeney, M. E., Roosevelt, K. A., Tang, Y., Pfafferott, K. J., McIntosh, K., Burchett, S. K., Mao, C., Walker, B. D., Goulder, P. J. R. (2003). Comprehensive Screening Reveals Strong and Broadly Directed Human Immunodeficiency Virus Type 1-Specific CD8 Responses in Perinatally Infected Children. J. Virol. 77: 7492-7501 [Abstract] [Full Text]  
• Scott, Z. A., Beaumier, C. M., Sharkey, M., Stevenson, M., Luzuriaga, K. (2003). HIV-1 Replication Increases HIV-Specific CD4+ T Cell Frequencies but Limits Proliferative Capacity in Chronically Infected Children. J. Immunol. 170: 5786-5792 [Abstract] [Full Text]  
• Al-Attar, I., Orav, E. J., Exil, V., Vlach, S. A., Lipshultz, S. E. (2003). Predictors of cardiac morbidity and related mortality in children with acquired immunodeficiency syndrome. J Am Coll Cardiol 41: 1598-1605 [Abstract] [Full Text]