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Previous Volume 345:1577-1578 November 22, 2001 Number 21 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Langerhans'-cell histiocytosis, previously called histiocytosis X, is an accumulation of dendritic Langerhans' cells and granulomatous lesions in various organs; its cause is unknown. The three-year survival rate among children with Langerhans'-cell histiocytosis has not improved during the past two decades and remains around 80 percent.¹ In children younger than two years old who have involvement of the liver, spleen, hematopoietic system, or lungs and who do not have a response to induction therapy over the course of six weeks, the probability of survival at three years is less than 20 percent.¹ We describe a child with Langerhans'-cell . . . [Full Text of this Article]

References

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• Tazi, A. (2006). Adult pulmonary Langerhans' cell histiocytosis.. Eur Respir J 27: 1272-1285 [Abstract] [Full Text]  
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• Sundar, K. M., Gosselin, M. V., Chung, H. L., Cahill, B. C. (2003). Pulmonary Langerhans Cell Histiocytosis: Emerging Concepts in Pathobiology, Radiology, and Clinical Evolution of Disease. Chest 123: 1673-1683 [Abstract] [Full Text]