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Previous Volume 345:1579-1580 November 22, 2001 Number 21 Next

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(American Heart Association Monograph Series.) Edited by Jesse E. Adams III, with Fred S. Apple, Allan S. Jaffe, and Alan H.B. Wu. 272 pp. Armonk, N.Y., Futura, 2001. $79. ISBN 0-87993-472-7.

Interest in biochemical markers in cardiology has increased tremendously in the past decade. Previously, biochemical markers were used mainly for retrospective verification of acute myocardial infarction. However, as more specific and sensitive markers of myocardial damage (e.g., troponin T and I) have become available, the focus has shifted to early diagnosis of myocardial damage, risk stratification, and selection of treatment. Furthermore, biochemical markers in cardiology are no longer equivalent to markers of myocardial damage. Markers of inflammation (e.g., C-reactive protein) and cardiac dysfunction (e.g., the natriuretic peptides) are already used in clinical practice. Markers of coronary artery disease, ischemia, and . . . [Full Text of this Article]

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