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Previous Volume 345:1777-1778 December 13, 2001 Number 24 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: The study by deVeber and colleagues (Aug. 9 issue),¹ which reported 12 deaths among 160 children with cerebral sinovenous thrombosis, raises important issues about the future treatment of such patients, since only 1 of the children received any type of fibrinolytic therapy (urokinase was used in a nonneonate). It is unclear whether this single patient benefited from treatment. Limited data show that local urokinase infusion can be a lifesaving treatment in children.²

I have successfully treated four young adults with cerebral-vein thrombosis by retrograde venous infusion of urokinase directly into the clot, with good outcomes in all. . . . [Full Text of this Article]

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