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Correspondence
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Volume 345:225 July 19, 2001 Number 3
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Pamidronate for Bone Pain from Osteolytic Lesions in Langerhans'-Cell Histiocytosis

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To the Editor: A 23-year-old woman with Langerhans'-cell histiocytosis presented with severe pain in the right iliac crest and right shoulder of three months' duration. The patient had undergone excision and radiation of a skeletal lesion of the left hip at the age of 10; diabetes insipidus had developed when she was 15; and she had been treated with mercaptopurine and prednisone at the age of 19. Skeletal-survey radiographs showed osteolytic lesions in the frontal bone of the skull and the right femoral head. Sustained-release morphine sulfate (60 mg twice daily) was prescribed, and the patient had partial relief of . . . [Full Text of this Article]

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