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Back pain developed in a 31-year-old man who had undergone total nodal irradiation and chemotherapy for Hodgkin's disease at the age of 15 years (when asymptomatic hilar adenopathy was found on a routine chest film) and who had received a second course of chemotherapy and radiotherapy at the age of 25 years for a recurrence of Hodgkin's disease in a cervical lymph node. Studies revealed a thoracic paravertebral mass in the previously irradiated field. After an extensive investigation revealed no other tumor sites, a thoracotomy was performed. Light-microscopical analysis of the tissue obtained showed that the tumor was composed of . . . [Full Text of this Article] |