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Correspondence
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Volume 345:467-469 August 9, 2001 Number 6
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Epilepsy

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To the Editor: In their review article on epilepsy, Browne and Holmes (April 12 issue)1 state that electroencephalographic studies should be performed 48 hours or more after a suspected seizure. We disagree. Studies of chronic partial epilepsy show that interictal epileptiform activity is more frequent after seizures (postictal activation).2 Sundaram et al.3 reported an increased probability of finding interictal discharges (up to 77 percent) when patients were studied within two days after a seizure. In a recent study of 300 consecutive patients with a first unexplained seizure in whom electroencephalography was performed within 24 hours after the seizure, epileptiform abnormalities . . . [Full Text of this Article]

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