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Correspondence
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Volume 345:543-545 August 16, 2001 Number 7
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Neurocognitive Function after Coronary-Artery Bypass Surgery

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To the Editor: Coronary-artery surgery remains the most scrutinized treatment used today. Associated neurocognitive dysfunction is of intense interest to medical professionals and the lay public. We feel compelled to address the shortcomings of the study by Newman et al. (Feb. 8 issue)1 and the accompanying editorial by Selnes and McKhann2 and to place the findings in the proper perspective.

The conclusions regarding neurocognitive dysfunction are limited by the highly selected population studied and the lack of controls. Confounding variables include the effects of general anesthesia, age, coexistent cerebrovascular disease, and the attendant decline in neurocognitive function independent of procedural . . . [Full Text of this Article]

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