To the Editor: A 57-year-old man presented with an ulcerative,acrallentiginous lesion on the sole of the left foot.Pathological examination showed a melanoma (Breslow depth, 2.2mm; Clark level IV) without involvement of the surgical margins;the dissected ilioinguinal nodes showed micrometastases. A computedtomographic (CT) scan did not show any other lesion. The patientreceived interferon alfa, but two years later, plantar and ilioinguinallesions recurred. They were removed twice in five months. Therapywith interferon alfa was stopped.
Two months later, a CT scan showed bilateral metastatic lesionsin the lung. The patient was treated with dacarbazine, . . . [Full Text of this Article]
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