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Correspondence
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Volume 346:65-67 January 3, 2002 Number 1
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Helicobacter pylori Infection and the Development of Gastric Cancer

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To the Editor: Uemura et al. (Sept. 13 issue)1 make an important contribution to our understanding of the complications of Helicobacter pylori infection, but I have a question regarding the ethics of their study. The authors enrolled 1526 patients, of whom 1246 had H. pylori infection. Of the H. pylori–positive patients, 297 had gastric ulcers and 275 had duodenal ulcers. Hence, 572 patients had a condition for which treatment to eradicate the H. pylori infection is indicated. The remaining H. pylori–positive patients had gastric polyps and nonulcer dyspepsia, conditions for which eradication treatment is not currently indicated.

Eradication . . . [Full Text of this Article]

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