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Perspective
Volume 346:954-955 March 28, 2002 Number 13
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Reperfusion Therapy in Acute Myocardial Infarction

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 by Stone, G. W.
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Coronary arterial occlusion due to thrombosis is the cause of most cases of myocardial infarction accompanied by ST-segment elevation. Rapid restoration of blood flow to jeopardized myocardium limits necrosis and reduces mortality. This can be accomplished medically, with a thrombolytic agent, or mechanically, with so-called primary balloon angioplasty or stenting (see figure). Each method has its advantages and limitations.

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Methods of Reperfusion in Patients with Acute Myocardial Infarction.

 
Thrombolytic therapy is widely available and effective, but its use is sometimes associated with bleeding complications. In 10 to 15 percent of patients who receive a thrombolytic agent, clot lysis is . . . [Full Text of this Article]


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