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Previous Volume 346:1241-1243 April 18, 2002 Number 16 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Infants with severe combined immunodeficiency are unable to mount an adaptive immune response, because they have a profound deficiency of lymphocytes. These babies usually die within a year from a sustained onslaught of opportunistic infections, but death can also be caused by immunization with live viral vaccines or with bacille Calmette–Guérin for the prevention of tuberculosis. Poliomyelitis, polioencephalitis, giant-cell pneumonia (caused by the measles virus), and fatal progressive vaccinia are other consequences of immunization of these infants. In fact, infants with severe combined immunodeficiency present a pediatric emergency to the physician; they can survive only if an immune system is . . . [Full Text of this Article]

References

Related Letters:

Gene Therapy for Severe Combined Immunodeficiency Disease
Handgretinger R., Koscielniak E., Niethammer D., Cavazzana-Calvo M., Hacein-Bey-Abina S., Fischer A.
Extract | Full Text | PDF  
N Engl J Med 2002; 347:613-614, Aug 22, 2002. Correspondence

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