To the Editor: In a 34-year-old woman with a history of alcoholabuse, cardiomyopathy, and AIDS, acute respiratory failure developedas a result of Escherichia coli sepsis and pneumonia. Initiallaboratory studies revealed a pH of 7.2, a bicarbonate levelof 8.8 mmol per liter, a partial pressure of carbon dioxideof 26 mm Hg, an anion gap of 15.4 mmol per liter, a lactatelevel of 6.9 mmol per liter, and a creatinine level of 1.8 mgper deciliter, with a normal blood sugar level and no ketones.
After four days of treatment, the patient's acidosis was worse(pH, . . . [Full Text of this Article]
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