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Previous Volume 346:1329-1331 April 25, 2002 Number 17 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Krystal et al. (Dec. 13 issue)¹ "found no evidence that naltrexone combined with psychosocial therapy was an effective treatment for alcohol dependence." We are concerned that the characteristics of the study sample may have made it difficult to detect significant differences among the treatment groups. Only 19 percent of the veterans initially evaluated were enrolled. In this extremely selected study sample, the results with naltrexone were similar to those without naltrexone. We were surprised that no significant differences were found among the study groups in the median number of days to relapse (176 days in the group . . . [Full Text of this Article]

References

This article has been cited by other articles:

• RUBIO, G., PONCE, G., RODRIGUEZ-JIMENEZ, R., JIMENEZ-ARRIERO, M. A., HOENICKA, J., PALOMO, T. (2005). CLINICAL PREDICTORS OF RESPONSE TO NALTREXONE IN ALCOHOLIC PATIENTS: WHO BENEFITS MOST FROM TREATMENT WITH NALTREXONE?. Alcohol Alcohol 40: 227-233 [Abstract] [Full Text]