This affection of the bronchia is always produced by chroniccatarrh, or by some other disease attended by long, violent,and often repeated fits of coughing.
R.T.H. Laënnec1
Bronchiectasis is an uncommon disease with the potential tocause devastating illness, including repeated respiratory infectionsrequiring antibiotics, disabling productive cough, shortnessof breath, and occasional hemoptysis. Landmarks in the historyof bronchiectasis include the vivid descriptions of patientswith suppurative phlegm that appeared in the writings of RenéThéophile Hyacinthe Laënnec in the early 19th century;the 1922 introduction by Jean Athanase Sicard of contrast bronchography,which permitted the precise imaging . . . [Full Text of this Article]
Pathophysiology
Focal and Diffuse Presentations
Causes
Infections
Primary Ciliary Dyskinesia
Immunodeficiency
Cystic Fibrosis
Rheumatoid Arthritis
Inflammatory Bowel Disease
Symptoms and Physical Findings
Diagnostic Testing
Pulmonary Function
Management
Acute Exacerbations or Bronchitis
Prevention or Suppression of Microbes
Bronchopulmonary Hygiene
Surgery
Hemoptysis
Prognosis
Conclusion and Revised Definitions
Source Information
From the Pulmonary and Critical Care Division, Department of Medicine, Oregon Health and Science University, Portland.
Address reprint requests to Dr. Barker at the Pulmonary and Critical Care Division, Department of Medicine, Oregon Health and Science University, Portland, OR 97201, or at barkera@ohsu.edu.
References
This article has been cited by other articles:
Burgel, P-R., Nadel, J. A.
(2008). Epidermal growth factor receptor-mediated innate immune responses and their roles in airway diseases. Eur Respir J
32: 1068-1081
[Abstract][Full Text]
Loebinger, M., Shoemark, A, Berry, M, Kemp, M, Wilson, R
(2008). Procalcitonin in stable and unstable patients with bronchiectasis. Chronic Respiratory Disease
5: 155-160
[Abstract]
Courtney, J., Kelly, M., Watt, A, Garske, L, Bradley, J, Ennis, M, Elborn, J.
(2008). Quality of life and inflammation in exacerbations of bronchiectasis. Chronic Respiratory Disease
5: 161-168
[Abstract]
Hasani, A, Chapman, T., McCool, D, Smith, R., Dilworth, J., Agnew, J.
(2008). Domiciliary humidification improves lung mucociliary clearance in patients with bronchiectasis. Chronic Respiratory Disease
5: 81-86
[Abstract]
Fuschillo, S., De Felice, A., Balzano, G.
(2008). Mucosal inflammation in idiopathic bronchiectasis: cellular and molecular mechanisms. Eur Respir J
31: 396-406
[Abstract][Full Text]
Eren, S., Esme, H., Avci, A.
(2007). Risk factors affecting outcome and morbidity in the surgical management of bronchiectasis. J. Thorac. Cardiovasc. Surg.
134: 392-398
[Abstract][Full Text]
Goss, C. H, Burns, J. L
(2007). Exacerbations in cystic fibrosis {middle dot} 1: Epidemiology and pathogenesis. Thorax
62: 360-367
[Abstract][Full Text]
Koff, J. L., Shao, M. X. G., Kim, S., Ueki, I. F., Nadel, J. A.
(2006). Pseudomonas Lipopolysaccharide Accelerates Wound Repair via Activation of a Novel Epithelial Cell Signaling Cascade. J. Immunol.
177: 8693-8700
[Abstract][Full Text]
Wenzel, R. P., Fowler, A. A. III
(2006). Acute Bronchitis. NEJM
355: 2125-2130
[Full Text]
Bilton, D., Henig, N., Morrissey, B., Gotfried, M.
(2006). Addition of Inhaled Tobramycin to Ciprofloxacin for Acute Exacerbations of Pseudomonas aeruginosa Infection in Adult Bronchiectasis.. Chest
130: 1503-1510
[Abstract][Full Text]
Ziedalski, T. M., Kao, P. N., Henig, N. R., Jacobs, S. S., Ruoss, S. J.
(2006). Prospective analysis of cystic fibrosis transmembrane regulator mutations in adults with bronchiectasis or pulmonary nontuberculous mycobacterial infection.. Chest
130: 995-1002
[Abstract][Full Text]
Santamaria, F., Montella, S., Camera, L., Palumbo, C., Greco, L., Boner, A. L.
(2006). Lung structure abnormalities, but normal lung function in pediatric bronchiectasis.. Chest
130: 480-486
[Abstract][Full Text]
Torrego, A, Haque, R A, Nguyen, L T, Hew, M, Carr, D H, Wilson, R, Chung, K F
(2006). Capsaicin cough sensitivity in bronchiectasis. Thorax
61: 706-709
[Abstract][Full Text]
Field, S. K., Cowie, R. L.
(2006). Lung Disease Due to the More Common Nontuberculous Mycobacteria. Chest
129: 1653-1672
[Abstract][Full Text]
Papi, A., Bellettato, C. M., Braccioni, F., Romagnoli, M., Casolari, P., Caramori, G., Fabbri, L. M., Johnston, S. L.
(2006). Infections and Airway Inflammation in Chronic Obstructive Pulmonary Disease Severe Exacerbations. Am. J. Respir. Crit. Care Med.
173: 1114-1121
[Abstract][Full Text]
Koh, W-J, Kwon, O J, Wilson, R, Wickremasinghe, M, Ozerovitch, L J, Davies, G, Wodehouse, T, Chadwick, M V, Abdallah, S, Shah, P
(2006). Bronchiectasis and non-tuberculous mycobacterial pulmonary infection * Authors' reply. Thorax
61: 458-458
[Full Text]
Rosen, M. J.
(2006). Chronic Cough Due to Bronchiectasis: ACCP Evidence-Based Clinical Practice Guidelines. Chest
129: 122S-131S
[Abstract][Full Text]
Wickremasinghe, M, Ozerovitch, L J, Davies, G, Wodehouse, T, Chadwick, M V, Abdallah, S, Shah, P, Wilson, R
(2005). Non-tuberculous mycobacteria in patients with bronchiectasis. Thorax
60: 1045-1051
[Abstract][Full Text]
Scheinberg, P., Shore, E., on behalf of the PC-TNDS-008 Study Group,
(2005). A Pilot Study of the Safety and Efficacy of Tobramycin Solution for Inhalation in Patients With Severe Bronchiectasis. Chest
127: 1420-1426
[Abstract][Full Text]
Koh, W.-J., Lee, K. S., Kwon, O J., Jeong, Y. J., Kwak, S.-H., Kim, T. S.
(2005). Bilateral Bronchiectasis and Bronchiolitis at Thin-Section CT: Diagnostic Implications in Nontuberculous Mycobacterial Pulmonary Infection. Radiology
235: 282-288
[Abstract][Full Text]
van Kessel, D. A., van Velzen-Blad, H., van den Bosch, J. M. M., Rijkers, G. T.
(2005). Impaired pneumococcal antibody response in bronchiectasis of unknown aetiology. Eur Respir J
25: 482-489
[Abstract][Full Text]
Tsang, K W, Tan, K C, Ho, P L, Ooi, G C, Ho, J C, Mak, J, Tipoe, G L, Ko, C, Yan, C, Lam, W K, Chan-Yeung, M
(2005). Inhaled fluticasone in bronchiectasis: a 12 month study. Thorax
60: 239-243
[Abstract][Full Text]
Field, S. K., Fisher, D., Cowie, R. L.
(2004). Mycobacterium avium complex Pulmonary Disease in Patients Without HIV Infection. Chest
126: 566-581
[Abstract][Full Text]
Patterson, J E, Bradley, J M, Elbom, J S
(2004). Airway clearance in bronchiectasis: a randomized crossover trial of active cycle of breathing techniques (incorporating postural drainage and vibration) versus test of incremental respiratory endurance. Chronic Respiratory Disease
1: 127-130
[Abstract]
Dupont, M., Gacouin, A., Lena, H., Lavoue, S., Brinchault, G., Delaval, P., Thomas, R.
(2004). Survival of Patients With Bronchiectasis After the First ICU Stay for Respiratory Failure. Chest
125: 1815-1820
[Abstract][Full Text]
Wolfgang, M. C., Jyot, J., Goodman, A. L., Ramphal, R., Lory, S.
(2004). Pseudomonas aeruginosa regulates flagellin expression as part of a global response to airway fluid from cystic fibrosis patients. Proc. Natl. Acad. Sci. USA
101: 6664-6668
[Abstract][Full Text]
Gibson, R. L., Burns, J. L., Ramsey, B. W.
(2003). Pathophysiology and Management of Pulmonary Infections in Cystic Fibrosis. Am. J. Respir. Crit. Care Med.
168: 918-951
[Abstract][Full Text]
Field, S. K., Cowie, R. L.
(2003). Treatment of Mycobacterium avium-intracellulare complex Lung Disease With a Macrolide, Ethambutol, and Clofazimine. Chest
124: 1482-1486
[Abstract][Full Text]
Murphy, T. F.
(2003). Immunity to Nontypeable Haemophilus influenzae: Elucidating Protective Responses. Am. J. Respir. Crit. Care Med.
167: 486-487
[Full Text]
King, P. T., Hutchinson, P. E., Johnson, P. D., Holmes, P. W., Freezer, N. J., Holdsworth, S. R.
(2003). Adaptive Immunity to Nontypeable Haemophilus influenzae. Am. J. Respir. Crit. Care Med.
167: 587-592
[Abstract][Full Text]