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Previous Volume 346:1405-1408 May 2, 2002 Number 18 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text PDF PDA Full Text Purchase this article Editorial by Slater, E. E. Letters Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited Related Article by Steinbrook, R. PubMed Citation

These are difficult times for the nation's system of protection for human subjects in research.^{1,2,3,4,5,6,7,8,9,10} On the basis of a series of reports, the Office of the Inspector General of the Department of Health and Human Services concluded that institutional review boards (IRBs) are now forced to "review too much, too quickly, with too little expertise," and with inadequate resources.⁶ One consequence is that there is minimal, often perfunctory, review of ongoing research. In addition, IRB members have become disillusioned as a result of both public criticism concerning the perceived failures of the boards and the increasing amount of time . . . [Full Text of this Article]

Origins of the Central Review Board

The Central Review Board and Facilitated Review

Early Experience with the Central Review Board

Future Challenges

References

Related Letters:

Institutional Review Board Reform
Emanuel E. J., Kornfeld D. S., Mann H., Paasche-Orlow M. K., Taggart J. C.
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N Engl J Med 2002; 347:1285-1286, Oct 17, 2002. Correspondence

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