The spectrum of acute mountain sickness ranges from mild, nonspecificsymptoms to high-altitude pulmonary edema and high-altitudecerebral edema. Most deaths from high-altitude illness occurwith high-altitude pulmonary edema, the risk of which is relatedto the rate of ascent, individual susceptibility, and the levelof exertion. Cold ambient temperature constitutes an additionalrisk factor. High-altitude pulmonary edema occurs worldwide,with the incidence peaking in the winter months because of skitourism. Mountain climbers and skiers who have had an episodeof high-altitude pulmonary edema are susceptible to unpredictablerecurrence when they are again exposed to high altitudes.
Salmeterol for the Prevention of High-Altitude Pulmonary Edema
Cruden N. L.M., Newby D. E., Webb D. J., Bärtsch P., Mairbäurl H., Basnyat B., Prodhan P., Noviski N. N., Kinane T. B., Swenson E. R., Maggiorini M., Scherrer U., Sartori C., Allemann Y.
Extract |
Full Text |
PDF
N Engl J Med 2002;
347:1282-1285, Oct 17, 2002.
Correspondence
This article has been cited by other articles:
Olivier, R., Scherrer, U., Horisberger, J.-D., Rossier, B. C., Hummler, E.
(2002). Lung Edema Clearance: 20 Years of Progress: Selected Contribution: Limiting Na+ transport rate in airway epithelia from alpha -ENaC transgenic mice: a model for pulmonary edema. J. Appl. Physiol.
93: 1881-1887
[Abstract][Full Text]
Cruden, N. L.M., Newby, D. E., Webb, D. J., Bartsch, P., Mairbaurl, H., Basnyat, B., Prodhan, P., Noviski, N. N., Kinane, T. B., Swenson, E. R., Maggiorini, M., Scherrer, U., Sartori, C., Allemann, Y.
(2002). Salmeterol for the Prevention of High-Altitude Pulmonary Edema. NEJM
347: 1282-1285
[Full Text]
