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A 43-year-old woman had sudden visual loss in her left eye. Syphilis had been detected serologically four years before, but she did not complete a course of medical treatment. Examination revealed markedly diminished visual acuity in the left eye. Biomicroscopy showed deep corneal edema and folds on Descemet's membrane only in the left eye (Panel A). Funduscopy revealed no abnormalities. A Venereal Disease Research Laboratory test was negative, and a fluorescent treponemal IgM and IgG antibody absorption test was positive (++++), as was a test for Treponema pallidum hemagglutination (+++; titer, 1:640) and a test for antibodies against borrelia (+). . . . [Full Text of this Article] |