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Previous Volume 346:1826-1829 June 6, 2002 Number 23 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Chasan-Taber and Stampfer (Dec. 20 issue)¹ state that there is increasing evidence that third-generation oral contraceptives are safer than previous formulations in terms of cardiovascular risk. Part of the evidence provided by Tanis et al. in the same issue² is a nonsignificant reduction in the risk of myocardial infarction among women who used third-generation oral contraceptives, as compared with those who used second-generation oral contraceptives (odds ratio, 0.5; 95 percent confidence interval, 0.2 to 1.1). However, the wide confidence interval highlights the low statistical power of the study and indicates that random variation may be an alternative . . . [Full Text of this Article]

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