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Clinical Practice
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Volume 346:175-179 January 17, 2002 Number 3
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Chronic Urticaria and Angioedema
Allen P. Kaplan, M.D.

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This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author's clinical recommendations.

A 35-year-old woman presents with a three-month history of daily generalized hives. The hives are pruritic, red wheals that range from 1.5 to 8.0 cm (0.5 to 3 in.) in diameter. She has frequent episodes of lip swelling and has also had three episodes of tongue swelling, one of which was associated with tightness of the throat. How should she be evaluated . . . [Full Text of this Article]

The Clinical Problem

Strategies and Evidence

Diagnosis

Evaluation

Therapy

            Histamine H1–Receptor Antagonists

            Combined H1- and H2-Receptor Antagonists

            Leukotriene Antagonists

            Sympathomimetic Agents

            Corticosteroids

            Experimental Therapies

Areas of Uncertainty

Guidelines

Summary and Recommendations


Source Information

From the Department of Medicine, Division of Pulmonary and Critical Care Medicine and Allergy and Clinical Immunology, and Konishi–Medical University of South Carolina Institute for Inflammation Research, Medical University of South Carolina, Charleston.

Address reprint requests to Dr. Kaplan at Medical University of South Carolina, Division of Pulmonary and Critical Care Medicine, Allergy and Clinical Immunology, 96 Johnathan Lucas St., Suite 812 CSD, P.O. Box 250623, Charleston, SC 29425, or at kaplana@musc.edu.

References


Related Letters:

Chronic Urticaria and Angioedema
Chowdhury B. A., Simonart T., Pfeiffer C., Kaplan A. P.
Extract | Full Text | PDF  
N Engl J Med 2002; 347:220-222, Jul 18, 2002. Correspondence

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