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Correspondence
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Volume 346:209-210 January 17, 2002 Number 3
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Prevention of Recurrent Variceal Bleeding

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To the Editor: Villanueva et al. (Aug. 30 issue)1 compared two treatments for recurrent bleeding from esophageal varices: endoscopic ligation and combined therapy with nadolol and isosorbide mononitrate. The initial dose of nadolol was 80 mg per day, and the mean (±SD) dose was 96±56 mg per day. In a review article in the same issue,2 Sharara and Rockey state that the initial dose of nadolol is 20 mg per day and the maximal dose is 80 mg per day. How many patients in the study by Villanueva et al. received doses of nadolol of more than 80 mg per . . . [Full Text of this Article]

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