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Correction to Israel et al., N Engl J Med 345(13):941-947 September 27, 2001.

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Volume 346:533-535 February 14, 2002 Number 7
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Bone Loss and Inhaled Glucocorticoids

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 by Israel, E.
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To the Editor: The study by Israel et al. (Sept. 27 issue)1 of bone thinning in women with asthma did not effectively control for the critical variables of the level of physical activity and the severity of asthma.

Comparisons between patients with mild asthma and those with persistent asthma who are receiving high doses of inhaled glucocorticoids must include a careful evaluation of base-line characteristics.2 Table 2 of the article shows that the 28 women who did not use inhaled glucocorticoids weighed less than the 42 women who required more than eight puffs of inhaled glucocorticoids per day (mean [±SD], . . . [Full Text of this Article]

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