Increased susceptibility to deep-vein thrombosis is a well-knownfacet of pregnancy and the puerperium, with the greatest riskoccurring during the puerperium. It remains unclear, however,whether a genetically determined tendency toward clot formationin the mother can affect the fetus or cause obstetrical complications.It is important to clarify this issue because mutations andpolymorphisms that contribute to a susceptibility to thrombosis— the inherited thrombophilias — occur in up to20 percent of persons of European descent.
In 1999, the Journal published a report on a case–controlstudy by Kupferminc et al., which showed that a hypercoagulablestate . . . [Full Text of this Article]
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