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Editorial
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Volume 347:756-758 September 5, 2002 Number 10
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HIV-1 Superinfection — A Word of Caution

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 by Jost, S.
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Acute human immunodeficiency virus type 1 (HIV-1) infection is typically associated with an influenza-like syndrome, with levels of virus in the bloodstream during the initial symptomatic period typically in excess of 10 million particles per milliliter.1 These acute symptoms usually resolve within one to two weeks, and there is a gradual reduction in viremia to a mean of about 30,000 particles per milliliter one year after infection.2 This dramatic drop in viremia is thought to be due to the induction of partially effective immune responses against the virus, although without treatment, viremia slowly rises over time. The conclusion that the . . . [Full Text of this Article]


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