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Previous Volume 347:759-761 September 5, 2002 Number 10 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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In 1963, before the advent of institutional review boards (IRBs), I was a young academic physician studying the regulation of sodium excretion by the kidneys. I paid medical students approximately $50 to serve as subjects for experiments involving only saline infusions and the collection of blood and spontaneously voided urine samples. I do not remember exactly what I told the students about the risks of the experiments but am quite certain that I characterized them as nominal. In one subject, severe phlebitis developed at the site of an intravenous infusion and required extensive therapy. The research project was funded by . . . [Full Text of this Article]

Conflicts of Interest and the Safety of Research Subjects

Management of Nonfinancial Conflicts of Interest

Related Letters:

Nonfinancial Conflicts of Interest in Research
Sollitto S., Youngner S., Lederman M. M.
Extract | Full Text | PDF  
N Engl J Med 2002; 347:2173, Dec 26, 2002. Correspondence

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